A Family Guy episode taking aim (it always takes aim) at Brody Jenner was prescient in its description of then-Bruce Jenner. The 2009 episode has Family Guy's Stewie feign revulsion that somebody like Brody could have emerged from the body of Olympian Bruce Jenner. (To be specific, Stewie says "I can't believe that came out of Bruce Jenner's vagina.")
Brian tries to enlighten Stewie, telling him "Bruce Jenner is a man." No, Brian, Stewie replies. "That's what the press would have you believe. Bruce Jenner is a woman, a beautiful Dutch woman." And that's six years before Annie Lebovitz snapped her famous shots of Caitlyn for Vanity Fair.
[Check out the "Most Interesting Finds" on Amazon ]